Misconceptions

[pamba]

@Baby Panay

Nice writing kid… You have a future here.

Naona huyu ni multi handler

[Nattydread]

@Mrs4thletter

I have seen people here narrate just how bad the side effects if PEP can get, but you take them like githeri?

PEP is not a one-shot pill like P2. It’s a full 28 days of a barrage of nauseating toxins daily. Sielewi how a person could take it routinely.

[system]

@Nattydread

barrage of nauseating toxins daily.

[Bakayaro]

@Luther12

Remember, PrEP is primarily aimed at discordant couples, at least in our local circumstances. We use two drugs, TDF/ 3TC or TDF/FTC while adult PEP uses four: TDF/3TC, ATV/r. Your guess is as good as mine on would have a lower incidence of resistance, all other factors held constant.

Doc, are any of these drugs AZT based or related?

[system]

@Bakayaro!

Doc, are any of these drugs AZT based or related?

AZT-based, no. AZT-related, yes. Masomo kidogo:

Major classes of ARVs are:

i. Entry/ Fusion Inhibitors e.g. Maraviroc, Enfuvirtide (Fuzeon), Vicriviroc, etc.

ii. Nucleoside Reverse Transcriptase Inhibitors (NRTIs) e.g Zidovudine (AZT), Stavudine (d4T), Lamivudine (3TC), Abacavir (ABC), Didanosine (ddI), Emtricitabine (FTC).

a slight chemical variation under this class are Nucleotide RTIs (N[SIZE=2]t[/SIZE]RTIs) e.g Tenofovir (TDF).

iii. Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) e.g Nevirapine (NVP), Efavirenz (EFV), Delavirdine, Etravirine.

iv. Integrase Inhibitors (INIs) e.g Dolutegravir, Elvitegravir, Raltegravir.

v. Protease Inhibitors e.g Atazanavir (ATV), Lopinavir (LPV), Amprenavir (APV), Ritonavir (RTV), Nelfinavir (NFV), Tipranavir (TPV), Fosamprenavir (FPV), Saquinavir (SQV), Indinavir (IDV), Darunavir (DRV).

[Bakayaro]

@Luther12

AZT-based, no. AZT-related, yes. Masomo kidogo:

Major classes of ARVs are:

i. Entry/ Fusion Inhibitors e.g. Maraviroc, Enfuvirtide (Fuzeon), Vicriviroc, etc.

ii. Nucleoside Reverse Transcriptase Inhibitors (NRTIs) e.g Zidovudine (AZT), Stavudine (d4T), Lamivudine (3TC), Abacavir (ABC), Didanosine (ddI), Emtricitabine (FTC).

a slight chemical variation under this class are Nucleotide RTIs (N[SIZE=2]t[/SIZE]RTIs) e.g Tenofovir (TDF).

iii. Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) e.g Nevirapine (NVP), Efavirenz (EFV), Delavirdine, Etravirine.

iv. Integrase Inhibitors (INIs) e.g Dolutegravir, Elvitegravir, Raltrgravir.

v. Protease Inhibitors e.g Atazanavir (ATV), Lopinavir (LPV), Amprenavir (APV), Ritonavir (RTV), Nelfinavir (NFV), Tipranavir (TPV), Fosamprenavir (FPV), Saquinavir (SQV), Indinavir (IDV), Darunavir (DRV).

Cheers bro. Had watched a few documentaries about AZT, aids, big pharma etc.
Bakayaro! is truly, edified.